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Antihistamines are mainly used to treat seasonal allergic rhinitis (hay fever), urticaria (hives), pruritus (itching) and insect bites and stings.They may also be used to help reduce nausea and vomiting, and in the emergency treatment of anaphylaxis - a severe allergic reaction.

dangers of non sedating antihistamines pubmed-67

The effects of these drugs on mood, daytime sleepiness, and some measures of sleep quality were assessed before and after one month of treatment.

Antihistamines are classified into two groups – the first-generation (“sedating”) and second-generation (“non-sedating”).

Sedating antihistamines cause sedation as they are highly lipid soluble and readily cross the blood brain barrier.

Antihistamines stop allergy symptoms by reducing or blocking histamines—chemicals the body releases in response to an allergic trigger.

Histamines cause the stuffy nose; itchy, watery eyes; and rashy skin that are the hallmarks of an allergic reaction.